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  • Critical guidelines
  • Azathioprine

    Reason: TPMT poor metabolizer (DPWG definition)
    Select alternative drug or reduce dose by 90%. Increase dose in response of hematologic monitoring and efficacy.
    Last guideline update: 2011-03-16 00:00:00
  • Mercaptopurine

    Reason: TPMT poor metabolizer (DPWG definition)
    Select alternative drug or reduce dose by 90%. Increase dose in response of hematologic monitoring and efficacy.
    Last guideline update: 2011-03-16 00:00:00
  • Thioguanine

    Reason: TPMT poor metabolizer (DPWG definition)
    Select alternative drug. Insufficient data to allow calculation of dose adjustment.
    Last guideline update: 2011-03-16 00:00:00

Show pharmacogenomic data

GenePhenotypeHaplotype 1Haplotype 2
TPMTPoor metabolizer*2*3A
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